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Spatial and temporal identification of malaria-endemic areas is a key component of vector-borne disease control. Strategies to target the most vulnerable populations, the periods of high transmission and the m...
Several studies have been conducted in Benin over the past two decades on insecticide resistance in mosquito vectors. These studies, by various authors, lead to diverse and scattered data. The present paper pr...
Malaria continues to pose a significant public health threat in northern Brazil. Current control strategies for Anopheles darlingi, the primary malaria vector in the Amazon region, depend on long-lasting insectic...
New malaria control tools are needed to prevent the transmission of parasites from the host to the mosquito vector and vice versa. The infectiousness of Plasmodium falciparum gametocytes obtained from individuals...
Africa bears the highest double burden of HIV and malaria worldwide. In 2023, an estimated 25.9 million people were living with HIV (PLHIV), and 246 million malaria cases were diagnosed in Africa. Malaria pati...
Undernutrition and severe malaria continue to be major public health concerns worldwide, particularly in African countries. While the association between malaria and malnutrition has been widely studied in var...
Gender-inclusive strategies are crucial for tackling vector-borne diseases in Africa, but most programs still overlook the lived experiences of local practitioners regarding cultural norms, power imbalances, g...
The recent emergence of artemisinin resistance in Africa is drawing scrutiny toward the use of alternative anti-malarial therapy based on Artemisia annua and Artemisia afra phytotherapies. This study aimed to det...
Continuous distribution of insecticide treated nets (ITNs) through schools is increasingly utilized by National Malaria Programmes across sub-Saharan Africa to maintain coverage between three-year mass distrib...
Targeted interventions are often needed to accelerate malaria elimination efforts. Mass screening and treatment (MSAT) involves testing all eligible and consenting individuals in an area for malaria and treati...
In a country with limited and unequally distributed resources, and plagued with malaria annually, under-five children are severely affected by this disease in Ghana. While the epidemiological burden of malaria...
Splenic infarction is an uncommon but serious side effect of Plasmodium vivax malaria, especially in young patients. Prompt diagnosis and effective treatment are essential to avoid serious consequences. Though th...
Effective malaria control requires accurate identification of Plasmodium infections to tailor interventions appropriately. Rapid diagnostic tests (RDTs) are crucial tools for this purpose due to their small size ...
Malaria remains a significant global health issue, with vector control strategies likes indoor residual spraying (IRS) and insecticide-treated nets (ITNs) show promise, socio-cultural and structural challenges...
As Namibia attempts to eradicate locally transmitted cases of malaria, epidemiological strategies, interventions, and outreach require a sound understanding of indigenous knowledge and practice. Research descr...
Malaria is a major public health problem in Nigeria. This study set out to ascertain Nigerian nurses' knowledge and willingness to recommend malaria vaccination to caregivers of under-5 children.
Expanding malaria community case management (mCCM) to all ages could shift the point-of-care to the community leading to improved healthcare access in underserved populations. This study assesses the economic ...
East Africa continues to bear a significant share of the global malaria burden, despite its commitment to the malaria elimination goal of 2030. Furthermore, reported variations in adherence to anti-malarials h...
Understanding the molecular mechanisms of the malarial parasites in hosts is crucial for developing effective treatments. Epitranscriptomic research on pathogens has unveiled the significance of RNA methylatio...
Histidine Rich Protein 2 (HRP2)/pan-Lactate Dehydrogenase (pLDH) combination rapid diagnostic tests (RDTs) may address the shortcomings of RDTs that detect HRP2 alone. However, the relative contribution of the...
Malaria poses a global threat to human health. It’s a vector-borne disease of public health concern and affects the socio-economic status of people in developing countries. Malaria management faces many challe...
Individuals experiencing recurrent malaria infections encounter a variety of alleles with each new infection. This ongoing allelic diversity influences the development of naturally acquired immunity and it can...
Malaria is a parasitic disease caused by protozoa of the genus Plasmodium, transmitted through the bites of Anopheles mosquitoes. Despite significant progress in malaria control, the disease remains a persistent ...
The original article was published in Malaria Journal 2025 24:26
Malaria and viral haemorrhagic fever (VHF) have overlapping symptomatology, creating clinical and diagnostic challenges within, and in travellers returning from, co-endemic areas. Rapid and accurate malaria di...
The malaria test positivity rate (TPR) is a key indicator for evaluating the effectiveness of malaria interventions. In Nigeria, routine data from January to June 2021 reported consistently high TPRs, ranging ...
Malaria control in African cities faces challenges mainly due to unplanned urbanization and the spread of Anopheles stephensi. Urbanization is changing malaria dynamics, driven by environmental changes and popula...
In sub-Saharan Africa, Plasmodium falciparum is the most prevalent species of malaria parasites. In endemic areas, malaria is mainly diagnosed using microscopy or rapid diagnostic tests (RDTs), which have limited...
The use of pre-referral injectable artesunate is among the strategies adopted to improve the outcome of childhood severe malaria in Nigeria. However, the extent of its implementation and impact on outcomes rem...
Western Province, Zambia experiences persistent and residual malaria transmission despite high household coverage of core vector control interventions. Standard vector surveillance, conducted overnight at hous...
The last malaria cases in near-elimination settings are often found in international border regions due to the presence of hard-to-reach populations, conflict, uneven intervention coverage, and human migration...
Progress in malaria control will rely on deployment and effective targeting of combinations of interventions, including malaria vaccines and perennial malaria chemoprevention (PMC). Several countries with PMC ...
Existing malaria control strategies for Plasmodium vivax are challenging due to its dormant and relapsing liver stages, as well as the early onset of gametocytogenesis. Primaquine (PQ) effectively eliminates dorm...
Perennial malaria chemoprevention (PMC) with sulfadoxine–pyrimethamine (SP) is recommended for children under 2 years of age living in areas of perennial malaria transmission. Initially delivered through the E...
Ghana adopted the WHO-recommended Seasonal Malaria Chemoprevention (SMC) in 2016 following a pilot study as a vital strategy for malaria control. SMC is the intermittent administration of a preventive and cura...
Though Ethiopia has made a remarkable effort towards malaria prevention and control activities, malaria is occurring at epidemic levels in different regions. In Tigray, the health system including the surveill...
Long-Lasting Insecticidal Nets (LLINs) are effective malaria prevention tools. However, information is limited about their durability and wash resistance in field circumstances, especially in seasonal transmis...
Despite a significant reduction in malaria cases in America, Venezuela has experienced a substantial increase between 2000 and 2019. Asymptomatic malaria, prevalent in both low- and high-endemic regions, poses...
Anopheles kleini is a competent vector mainly observed in the northern, malaria-risk areas of the Republic of Korea (ROK). In this study, the population genetic structure of An. kleini was analysed for the first ...
Interventions against adult Anopheles mosquitoes responsible for malaria transmission have traditionally been aimed at indoor spaces and biting behaviours. However, no globally recommended intervention exists whi...
Asymptomatic malaria poses a significant challenge to malaria eradication efforts and delays global elimination strategies. Mixed infections are also a major concern, as they frequently relapse, increase the r...
Mathematical modelling plays a crucial role in understanding malaria epidemiology and evaluating anti-malarial interventions. In sub-Saharan Africa, National Malaria Control Programs are increasingly collabora...
Despite the implementation of different control interventions, Plasmodium parasite infections in the communities (among asymptomatic and symptomatic individuals) still play a crucial role in sustaining malaria tr...
Microsporidia MB is a naturally occurring symbiont in Anopheles arabiensis mosquitoes that inhibits the development of Plasmodium. It is transmitted both vertically and horizontally, enabling its spread within mo...
Malaria has been surging in India for the past 3 years after reaching the recorded low in 2021. Among the possible reasons for this unexpected surge of cases, such as insufficient surveillance, slow and aggreg...
The World Health Organization-approved Anopheles interventions target indoor biting and resting behaviour, but are impractical or inapplicable in some settings. In Jambi Province, Sumatra, Indonesia, local indige...
In polyclonal human malaria infections, the roles of individual clones in human-to-mosquito transmission and their relative transmissibility remain poorly understood. In addition, mutations conferring drug res...
Malaria, a mosquito-borne disease, is a serious public health issue globally and a leading cause of morbidity and mortality in many developing countries worldwide. Cambodia is in the last stages of malaria eli...
Rapid diagnostic tests (RDTs) used to diagnose Plasmodium falciparum predominantly target the antigen Histidine Rich Protein 2 (HRP2) exclusively. With the emergence of hrp2/hrp3 gene deletions, RDTs targeting ot...
This work investigated the future (2021–2050) impact of Climate Change on Malaria Prevalence in the Upper River Region of The Gambia under two representative concentration pathways, RCP4.5 and RCP8.5, comparin...
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