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This work investigated the future (2021–2050) impact of Climate Change on Malaria Prevalence in the Upper River Region of The Gambia under two representative concentration pathways, RCP4.5 and RCP8.5, comparin...
Progress in malaria elimination has been hindered by recent changes in mosquito behaviour and increased insecticide resistance in response to traditional vector control measures, such as indoor residual sprayi...
Plasmodium falciparum is the main cause of malaria in North-Eastern (NE) states of India. Artemether–lumefantrine (AL) was introduced as first-line therapy against uncomplicated P. falciparum cases in 2013 after ...
Malaria elimination, defined as interrupting local transmission and reducing cases to zero, is a critical public health goal. While a dual parasite-vector approach is essential, the path to elimination is comp...
To reduce malaria burden in Côte d'Ivoire, the Ministry of Health aims for 90% of its population to possess one long-lasting insecticidal net (LLIN) for every two persons by 2025. This study evaluated LLIN cov...
Malaria is a leading cause of illness and death among children under-five in sub-Saharan Africa, with Nigeria bearing the highest global malaria burden. Despite interventions such as insecticide-treated nets a...
Seasonal malaria chemoprevention (SMC) with sulfadoxine-pyrimethamine and amodiaquine (SP + AQ) involves the monthly administration of therapeutic doses to children under five years of age during periods of hi...
Subpatent Plasmodium falciparum infections, defined as infections with parasite density below the detection limit of routine malaria diagnostic tests, contribute to infectious reservoirs, sustain transmission, an...
Malaria transmission in Sierra Leone is intense and perennial, accounting for 40% of clinical consultations. Medical workers diagnose suspected malaria cases using rapid diagnostic tests (RDT) and microscopy, ...
Since SARS-CoV-2 has caused unprecedented changes in the epidemiology of other infectious diseases, investigations on coinfection between SARS-CoV-2 and one of the famous vector-borne diseases, malaria, are cr...
Malaria remains a significant public health concern in Yemen, ranking fourth in incidence within the Eastern Mediterranean Region. Community pharmacists play a pivotal role in malaria management and often disp...
Malaria remains a significant global health threat, with sub-Saharan Africa (SSA) bearing the highest burden of the disease. Plasmodium falciparum is the predominant species in the region, leading to substantial ...
Forest-exposed populations remain the last significant, and most difficult to access, high-risk populations for malaria in Cambodia. Despite the availability of long-lasting insecticidal nets (LLINs) and/or ha...
Microsporidia MB, a naturally occurring Anopheles symbiont was shown to strongly impair Plasmodium transmission without imposing deleterious fitness effects on larval development, fecundity, adult survival, and a...
The World Health Organization (WHO) recommends parasite-based diagnosis of malaria before treatment. The use of nucleic-acid amplification (NAAT) for detection of Plasmodium spp. has expanded rapidly in recent ye...
The Zanzibar Malaria Elimination Programme relies on insecticide-treated nets as the principal vector control method, supplemented by reactive focal indoor residual spraying. Despite the success, local malaria...
Malaria remains the leading parasitic disease worldwide with a significant global morbidity and mortality burden. Plasmodium malariae, the least prevalent of the five Plasmodium species that cause human malaria, ...
Malaria poses a significant public health burden globally, particularly in Burundi, where it is the leading cause of mortality and morbidity. To eliminate malaria, the malaria vaccine will be introduced in chi...
Since 2017, the first-line treatment for uncomplicated Plasmodium falciparum infection in Ethiopia has been artemether-lumefantrine (AL), plus a single dose of primaquine (PQ). The World Health Organization (WHO)...
The World Health Organization (WHO) has called for new malaria vaccines with > 90% efficacy against Plasmodium falciparum infection to expand the anti-disease benefit provided by the RTS,S/AS01 and R21/Matrix M s...
Strengthening malaria control and expediting progress toward elimination requires targeting gametocytes to interrupt transmission. Artemisinin-based combination therapy (ACT) effectively clears Plasmodium falcipa...
Malaria is a major public health problem in Tanzania, accounting for 3.1% of the global cases, with under-five children being particularly vulnerable. Over half of malaria deaths in Tanzania occurred among und...
Increasing unplanned urbanization in tropical Africa may create new niches for malaria vectors, raising transmission risk, yet control efforts focus on rural ecosystems. Understanding mosquito diversity, ecolo...
Attractive targeted sugar baits (ATSBs) are a potential addition to an integrated vector management strategy against malaria. ATSB stations, which include a sugar bait and an ingestion toxicant, could potentia...
Malaria remains a significant public health challenge, particularly in sub-Saharan Africa, where it accounts for high morbidity and mortality rates. Sierra Leone, including Port Loko District, continues to exp...
The physical integrity of insecticidal-treated nets (ITNs) is important for creating a barrier against host-seeking mosquitoes and, therefore, influences people's perception of the net's effectiveness and thei...
The main malaria vector control methods implemented in Mozambique are insecticide-treated nets (ITN’s) and indoor residual spraying (IRS). These insecticide-based interventions are currently threatened by the ...
Information on the status of insecticide resistance in malaria vectors is critical for implementing effective malaria vector control. The Sierra Leone National Malaria Control Programme, in collaboration with ...
Assessing the acceptability of new malaria control interventions in clinical trials can be complex due to the need for strict ethical standards and specific trial procedures. While in-depth interviews and focu...
Understanding the emergence and spread of anti-malarial resistance, particularly to artemisinin and its partner drugs, is essential for eradicating malaria in worldwide. To identify genetic markers associated ...
Anaemia is a deleterious consequence of malaria, and its accurate diagnosis is crucial for effective management. However, laboratory methods for measuring haemoglobin (Hb) concentration, like the Coulter Count...
Uganda grapples with a considerable anaemia-malaria-fever burden, reporting approximate prevalence rates as high as 33%, 34%, and 37% in specific regions. In recent years, attempts have been made by the Minist...
Malaria continues to be a significant public health issue in Nigeria, which bears the highest burden of the disease globally. This study examined the prevalence and determinants of insecticide-treated net (ITN...
Despite advances in malaria chemotherapy, the disease continues to claim thousands of lives annually. Addressing this issue requires the discovery of new compounds to counteract resistance threatening the curr...
Defining antibody correlates of protection against clinical malaria in areas of low and unstable transmission is challenging because of limited malaria cases in these areas. Additionally, clinical malaria affe...
Insecticide resistance amongst vector populations is a major challenge, exacerbated by the continued use of the same active ingredients. The present study assessed the impact of long-lasting insecticidal nets ...
Active surveillance involves systematically monitoring patients to seek detailed information about the occurrence of adverse events (AEs) following drug administration. The Seta technology was developed to imp...
The original article was published in Malaria Journal 2024 23:403
Malaria, which affects over half of the world’s population, is controlled through clinical interventions and vector control strategies. However, these efforts are threatened by resistance to anti-malarial drug...
Malaria remains a significant health issue in Rwanda. Primary malaria prevention methods include insecticide-treated nets and indoor residual spraying as core interventions. Mosquito repellents, larval source ...
Malaria presents a disproportionate threat to pregnant women, making access to malaria prevention tools crucial for controlling the disease in this vulnerable population.
Artemisinin-based combination therapy (ACT) remains a broadly effective anti-malarial drug combination, but the emergence of resistance is threatening its effectiveness. Limiting the spread of these drug-resis...
Malaria is a critical global health issue, particularly for children in endemic regions. However, factors associated with recurrent severe malaria in children under 5 years of age in Northern Uganda are poorly...
The genetic diversity of malaria parasites varies between regions in the world. The genetic polymorphisms of the genes Pvs48/45 and Pvs47 which encode gametocyte/gamete proteins of Plasmodium vivax, were studied ...
In the context of high malaria burden yet limited resources, Guinea’s national malaria programme adopted an innovative subnational tailoring (SNT) approach, including engagement of stakeholders, data review, a...
Thrombocytopenia is a common haematological abnormality in malaria patients that is associated with an increased risk of mortality. Given the endemic nature of malaria in Ethiopia, it is crucial to comprehend ...
Malaria occurred endemically in Germany until the twentieth century. Climate change and globalization are known to promote the spreading of malaria. Erlangen is a city with just under 120,000 inhabitants locat...
Cambodia strives to eliminate all species of human malaria by 2025, requiring that foci among forest-exposed populations in remote settings be addressed. This study explores malaria risks amongst forest-expose...
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