Table 5 Summary of reported results for early parasitological response

7

AL or DP

TS

1

Percentage positive

58.3

60.5

RR

0.97 (0.72–1.31)

0.84

AL or DP

TS

2

Percentage positive

19.4

5.0

RR

3.87 (1.85–8.12)

 < 0.001

9

AL

EFV or NVP

2

N (%) positive

9 (5.3)

171

AL

LPV/r

2

N (%) positive

9 (8.4)

107

AL

EFV or NVP

3

N (%) positive

2 (1.2)

171

AL

LPV/r

3

N (%) positive

2 (1.9)

105

11

AL

EFV or NVP or LPV/r

3

Median (IQR) HL(h)

3.51 (2.98–4.03)

22

2.8 (2.38–3.36)

77

0.003

12

AL or SP

None

3

N/A

N/A

N/A

OR

1.15

0.6

17

AL

EFV

N/A

Median (range) PC50 (h)

5.7 (0.3–25.8)^a

57

AL

EFV

N/A

Median (range) PC90 (h)

13.8 (2.9–32.9)^a

57

18

DP

EFV

N/A

Median (range) PC50 (h)

4.2 (0.6–40.3)

84

DP

EFV

N/A

Median (range) PC90 (h)

10.1 (3.2–63.1)

84

DP

EFV

N/A

Median (range) HL (h)

2.2 (1.2–9.8)

84

DP

EFV

N/A

N (%) HL > 5.5 h

5 (6.0%)

84

DP

NVP

N/A

Median (range) PC50 (h)

3.1 (0.2–10.3)

46

DP

NVP

N/A

Median (range) PC90 (h)

8.2 (2.4–19.7)

46

DP

NVP

N/A

Median (range) HL (h)

2.1 (1.1–6.8)

46

DP

NVP

N/A

N (%) HL > 5.5 h

1 (2.2%)

46

19^b

AL

NVP, EFV

3

N (%) positive

8 (11.8)

68

12 (12.1)

99

0.944