Enhancing safety of rapid and accurate malaria diagnosis in patients at risk for viral haemorrhagic fever

Malaria Journal

Table 2 Technical detection limits of the Alethia Malaria LAMP assay and the EasyNAT Malaria CPA in mixtures of patient whole blood with Plasmodium falciparum and DNA/RNA Shield buffer

Parasite density^a (Parasites/μL)	Results
Parasite density^a (Parasites/μL)	Alethia Malaria LAMP assay	EasyNAT Malaria CPA
5	+	+
0.5	+	+
0.05	+	+
0.005	+	+
0.0005	−	−
0.00005	−	−

LAMP loop-mediated isothermal amplification, CPA cross-primer assay
^aIn whole blood of a patient with P. falciparum malaria diluted with uninfected blood and mixed with DNA/RNA Shield buffer

ISSN: 1475-2875