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Table 4 Membrane feeding assay at the baseline and day 42 in Arjo-Didessa sugar development site and its surrounding, southwest Ethiopia (2019–2022)

From: Effect of low-dose primaquine treatment on Plasmodium vivax recurrence and transmission-blocking activity in southwest Ethiopia: a longitudinal cohort study

Characteristics

CQ

CQ + PQ

Baseline

n = 19

Day 42

n = 19

Baseline

n = 20

Day 42

n = 20

Age (in years), n (%)

 Median

18

18

21

21

 Mean ± SD

23.0 ± 9.8

23.0 ± 9.8

24.7 ± 12.6

24.7 ± 12.6

 5–15

4 (21.0)

4 (21.0)

6 (30)

6 (30)

  > 15

15 (78.9)

15 (78.9)

14 (70)

14 (70)

Sex, n (%)

 Female

5 (26.3)

5 (26.3)

6 (30)

6 (30)

 Male

14 (73.7)

14 (73.7)

14 (70)

14 (70)

Asexual parasite/μL (geometric mean) 95%CI

3366 (1823–6211)

6332 (4167–9623)

4710 (2631–8431)

948 (454–1976)

Gametocytes/μL (geometric mean) 95%CI

544 (329–899)

737 (397–1369)

415 (254–675)

159 (55–457)

No. of gametocyte positive individuals

19 (100.0)

7 (36.8)

20 (100.0)

5 (25.0)

Mosquitoes

 Exposed

1700

1614

1584

1464

 Fed

1093

1101

918

722

Patient infectious to mosquito, n (%)

19 (100)

14 (73.6)

20 (100)

10 (50.0)

Infected mosquitoes, n (%)

356/710 (50.1)

250/684 (36.5)

275/632 (43.5)

86/400 (21.5)

Mean oocyst/mosquito (range)

34.0 (1–216)

20.6 (0–214)

43.6 (1–215)

5.3 (0–82)

Range of oocyst intensity

33–2974

0–1548

14–3725

0–423