Fig. 3

Molecular comparison of parasite clones in human infections and mosquito midguts post-feeding. A Differential prevalence of the Pfcsp and Pftrap haplotypes in the human and mosquito samples. Roman numbers represent the haplotypes in Fig. 2 haplotype networks. Error bars (representing 95% CI) and annotations are presented for haplotypes with at least 10% prevalence in either population. B Percentage of transmitting haplotypes and species-exclusive haplotypes when comparing human and mosquito samples at each timepoint (e.g. comparing haplotypes from day 2 human blood samples with haplotypes from infected midguts of mosquitoes that fed on the same day 2 blood material). C Percentage of transmitting haplotypes and species-exclusive haplotypes when comparing baseline mosquito samples to human samples at each timepoint (e.g. comparing haplotypes from day 2 human blood samples with haplotypes from infected midguts of mosquitoes that fed on day 0 blood material). D The percentage of total reads that transmitting and non-transmitting haplotypes encompass at each timepoint when comparing human and mosquito samples at each timepoint and E when comparing baseline mosquito samples to the human blood samples at each timepoint