Table 6 Binding affinities (in kJ/mol) of the identified compounds toward the selected CYP enzymes according to molecular docking studies
Plant | Compound/Enzyme | CYP4G17 | CYP6M2 | CYP6P3 | CYP6P9a | CYP9J3 |
|---|---|---|---|---|---|---|
P. amalago var. amalago | Piperine |  − 39.7 |  − 35.6 |  − 38.5 |  − 36.4 |  − 31.0 |
C. verticillata | 2,3-Diacetoxytormentic acid |  |  |  |  − 44.4 |  |
K. pinnata | Bryophyllin A |  − 42.3 |  − 44.4 |  − 47.7 |  |  − 39.3 |
K. pinnata | Bryophyllin C |  − 31.8 |  − 46.9 |  − 49.4 |  |  − 39.3 |
K. pinnata | Luteolin-7-O-β-d-glucoside |  − 36.4 |  − 46.0 |  − 43.9 |  |  − 37.2 |