Emerging threat of artemisinin partial resistance markers (pfk13 mutations) in Plasmodium falciparum parasite populations in multiple geographical locations in high transmission regions of Uganda

Table 3 Regional variation of Pfk13 mutations

Mutation	Status	Acholi (n = 59) (%)	Karamoja (n = 60) (%)	Lango (n = 60) (%)	West Nile (n = 59) (%)	P value
Wild Type	Present	47 (79.6)	41 (68.3)	45 (75.0)	58 (98.3)	0.002^$
	Absent	12 (20.3)	19 (31.7)	15 (25.0)	1 (0.0)
C469Y	Present	8 (13.6)	14 (23.3)	9 (15.0)	1 (1.7)	0.007^$
	Absent	51 (86.4)	46 (76.7)	51 (85.0)	58 (98.0)
S522C	Present	0 (0.0)	0 (0.0)	1 (1.7)	0 (0.0)	1.000*
	Absent	59 (100.0)	60 (100.0)	59 (98.3)	59 (100.0)
A675V	Present	4 (6.8)	4 (6.7)	5 (8.3)	0 (0.0)	0.095*
	Absent	55 (93.2)	56 (93.3)	55 (91.7)	59 (100.0)

ISSN: 1475-2875