Fig. 4

GHPB single point screen. Compounds were tested at 1 µM against (A) the P. berghei liver schizonts and (B) HepG2 cells culture in galactose media. C For confirmation, 35 compounds, including 6 hits with > 80% inhibition of P. berghei liver schizonts and < 15% inhibition of HepG2 cells (lower right quadrant), were resupplied for dose–response assays